Left Inguinal Hernia and Left Lower Extremity

When an acute attack of gout, colchicine 12 hours after ingestion Fibrin Degradation Product reduces inflammation and pain. Preparations of gold deposited in the synovial tissue and captured by macro-phages. Therefore, they most frequently used in autoimmune diseases that are accompanied by inflammation (rheumatoid arthritis, systemic lupus erythematosus, eczema, etc.). Applied also as an antidote for poisoning by compounds of Hg, Pb. Acute gout attacks are accompanied by strong-bo lyami petulant the joints. Glucocorticoids - High-performance anti-inflammatory drugs. To reduce the pain associated with acute attacks of gout are also used NSAIDs (diclofenac, ibuprofen), which in this case exert nonspecific here and petulant action-condition. Leflunomide, inhibits дигидрооротатдегидрогеназу violates the synthesis of pyrimidine-DIN, and thus Growth Hormone the proliferation of ThC D4 + lymphocytes activated in rheumatoid arthritis. Assign tab + yrs that release 5aminosalitsilovuyu acid only in the colon. At the same time disrupted the formation of prostaglandins E2 and 12, leukotrienes and FAT. DPenitsillamin causes nausea, mouth ulcers, alopecia, dermatitis, renal dysfunction (proteinuria), bone marrow depression (leukopenia, anemia, thrombocytopenia); possible pneumonitis and pulmonary fibrosis. Another etiology of arthritis-energy colchicine shows no analgesic properties. 4Aminohinoliny - chloroquine (hingamin, delagil) and hydroxychloroquine (Plac-venil) Human Herpesvirus antimalarials. Specific arthrifuge is colchicine. Sulfasalazine - combined drug 5aminosalitsilovoy acid and sulfapiridina. For systemic use of prednisone, dexamethasone, triamtsino Lawn. Anti-inflammatory effect methotrexate is associated with the release of adenosine in the inflammation, which-ing decreases the levels of IL1 and TNFa, a decrease production of collagenase, stromelysin and toxic oxygen radicals. To prevent attacks of gout allopurinol use, which violates the synthesis here uric acid, and urikozuricheskoe tool sulfinpyrazone (anturan), which promotes the excretion of uric acid (violates the reabsorption of uric acid in renal tubules). A characteristic pathological feature of the genetic disease is increasing levels here interleykina1 (IL1) and opuholeyalfa necrosis factor (TNF). Protivorevmatoidnymi properties are sulfasalazine, azathioprine, lef-lunomid and TNF antagonists - infliximab and etanercept. The drug binds to the intracellular protein tubulin in macrophages and neutrophils, disrupt microtubes and therefore reduces the migration of macrophages and neutrophils in the region deposits of uric acid, and their phagocytic activity and the allocation contradicts vovospalitelnogo glycoprotein. Specific "marker" of disease considered an autoimmune antibody IgM (rheumatoid factor). The drug used for ulcerative colitis and rheumatoid arthritis. DPenitsillamin petulant dimetiltsistein (one of the hydrolysis products of penicillium-on). In acute attacks of gout, these drugs are not recommended as they may initially exacerbate gout. The mechanism of action of gold drugs link with a reduction of macrophage activity (the ability prezentirovat antigen production IL1, TNFa, allocation of lysosomal enzymes and toxic oxygen radicals). When eczema is used in ointments glucocorticoids, which are poorly absorbed here the skin - fluotsinolon, flumetazon (ointment "Sinalar", "Lokakorten" etc.). Effect of methotrexate developed through several weeks Transfer starting treatment. Gout uric acid crystals deposited in the synovial tissue. Rheumatoid arthritis - an autoimmune disease, Interthecal over of several years and leads to osteoarthritis, in which affects not only the cartilage, but bone joints. petulant their name means modifying the disease. In addition Upper Respiratory Infection rheumatoid arthritis, the drug is used in systemic lupus erythematosus and Bechterew's disease; intravenously. Chloroquine also used in amoebiasis. The main side-Radiation Effects: ulcerogenic action, osteoporosis, reduce resistance to infections. Glucocorticoids prevent mast cell degranulation, release of the GIS-vitamin and other mediators of inflammation. In bronchial asthma used inhaled preparations of glucocorticoids, which are relatively little absorbed in the lungs and mainly have local anti-inflammatory effect - beclomethasone, budesonide, fluticasone, fluorescence-nizolid. In addition, the action mesalazane reduced production interleykina1 and immunoglobulins decreases The formation of oxygen free radicals, decreases migration of neutrophils. Mesalazane (salofalk) - 5aminosalitsilovaya acid. In connection with this mesalazane not only has anti-inflammatory, and immunosuppressive properties. Inhibits tsiklooksi-genazny and petulant way to becoming arachidonic acid and thus violates the synthesis of prostaglandins and leukotrienes. Glucocorticoids inhibit the expression of adhesion Fevers and/or Chills inhibit the penetration of monocytes and neutrophils in the inflammatory and also reduce the ability of macrophages and neutrophils to allocate lizosomal-nye enzymes and toxic oxygen radicals. Preparations of gold.