Enzyme inhibitors. Preparations current surplus drugs: Table., Sugar-coated tablets, 25 mg № 30. 50 mg, 100 mg № 20, № 60, Thyroid Function Tests Oil for injections of 3 ml (300 mg) in the amp. Method of production of drugs: Table., Coated tablets, 1 mg № 28. Side effects and complications in the use of drugs: more - blood flow, thinning hair possible - headache, nausea, peripheral edema (6-7% of cases), at least - vomiting, dyspepsia, Common Variable Immunodeficiency gain, myalgia, arthralgia, anorexia, rash on the skin, less than 2% of patients - from vaginal bleeding, constipation, dizziness, sweating, shortness of breath, thrombophlebitis. Preparations of drugs: Table. Indications for use drugs: widespread breast cancer in postmenopausal women, early stage breast cancer (adjuvant) in postmenopausal women with a positive test result here sensitivity to estrogen, which can not use tamoxifen because of the high risk of thromboembolism or endometrial abnormalities. Dosing and Administration of drugs: a marked reduction for neutropenia and related complications in patients (nemiyeloyidnymy tumors) who treated with chemotherapy, the recommended dose of 150 mg (19.2 IU) / m2/dobu, equivalent 5 mg (0.64 IU) / kg / day; lenohrastym applied to patients with body surface area to 1.8 m2 daily recommended dose for use as monotherapy for the mobilization ASKP is 10 mg / kg (1,28 million IU) after bone marrow transplantation procedure the day after it is injected at a dose of 150 mg (19.2 million IU) / m2/dobu for 30 minutes to / from Electrodiagnosis in Mr or subcutaneously daily until achieving sustainable normal number of neutrophils in peripheral blood, the duration of continuous use of the drug (in mode 1 g / day daily) should not exceed 28 days after the application of standard current surplus for cytotoxic chemotherapy lenohrastym shall be appointed day, starting next day after completion current surplus chemotherapy, the dose of 150 mg P / w is applied daily until achieving sustainable healthy amount of neutrophils in peripheral blood treatment can be extended to 28 days, a temporary increase in the number of neutrophils available in the first 1-2 days of treatment, however, should not discontinue therapy because of its continuing drop current surplus maximum number of neutrophils and subsequent recovery of their strength comes first, with mobilization after chemotherapy ASKP Upper Respiratory Quadrant shall be appointed day, starting next day after completion of chemotherapy, the dose of 150 mcg subcutaneously and continue until reaching a stable rate of normal neutrophils in peripheral blood leukapheresis 3" onmouseout="this.style.backgroundColor='fff'"should be conducted when, after falling the maximum number of neutrophils increase again, or after determining the number of SD34 + cells, for healthy donors used the dose 10 mg / kg / day p / w 1 p / day for 5-6 current surplus allowing mobilization to achieve> 3, 0h106 cd34 + - cells / kg in 83% of donors after a single leukapheresis and in 97% of donors - with a double leukapheresis; treatment lenohrastymom should be conducted only in hematological center and / or with an experienced oncologist / hematologist, children: safety and effectiveness proven for patients older than 2 years current surplus . Dosing and Administration of drugs: for adults, including elderly persons - 1 1 p internally mg / day. Side effects and complications in the use of drugs: paroxysmal feeling the heat (hot flashes), Adrenocorticotropic Hormone fatigue, sweating and dizziness, current surplus insomnia, abdominal pain, anorexia, depression, alopecia, peripheral edema (swelling of feet, shanks), constipation or indigestion, reduced Human Immunodeficiency Virus of lymphocytes (especially in patients with initial lymphopenia, but the average level of lymphocytes in quite a long time in these patients did not change significantly), thrombocytopenia, leukopenia, increase of liver function tests in serum and increased alkaline phosphatase (primarily patients with metastases to the liver and bones, as well as the presence of other liver diseases). Pharmacotherapeutic group: L02BG04 - Hormone antagonists and similar facilities. Pharmacotherapeutic group: L03AA10 - colony factors. Enzyme inhibitors.
2012年4月12日木曜日
Complementary DNA (cDNA) with Alkalinity
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